Understanding Pulmonary Embolism (PE): Symptoms, Risks & How Minimally Invasive Thrombectomy Saves Lives | Fabio Komlos MD
FABIO KOMLOS, MD
Interventional Radiology • Minimally Invasive Solutions

Understanding Pulmonary Embolism (PE): Symptoms, Risks & How Minimally Invasive Thrombectomy Saves Lives

Written by the Education Team
At Fabio Komlos, MD, we're dedicated to making complex medical concepts easier to understand—because the more you know, the better decisions you can make about your health. Today, we're breaking down a serious but often misunderstood condition: Pulmonary Embolism (PE). PE can be life-threatening, but with rapid diagnosis and modern minimally invasive treatments like catheter-based thrombectomy, outcomes are better than ever.

As an Interventional Radiologist and Medical Director with extensive expertise in pulmonary emboli and deep venous thrombosis, Dr. Fabio Komlos specializes in delivering advanced, image-guided procedures that remove dangerous clots quickly and safely.

What Is a Pulmonary Embolism (PE)?

A pulmonary embolism occurs when a blood clot—most often from the deep veins in the legs (deep vein thrombosis, or DVT)—travels through the bloodstream, moves through the heart, and becomes lodged in the arteries of the lungs. This blockage restricts blood flow, preventing the lungs from oxygenating the body and placing immense stress on the right ventricle, the chamber responsible for pumping blood into the lungs.

While the left ventricle pumps blood to the entire body, the right ventricle is smaller—so when a large clot suddenly obstructs the pulmonary artery, the right side of the heart can quickly fail. This is why PE is a true medical emergency.

Critical Statistics:

  • PE is the third leading cause of cardiovascular death, behind heart attacks and strokes
  • Up to 900,000 people in the U.S. experience venous thromboembolism (VTE) each year
  • 60,000–100,000 cases are fatal annually

Common Symptoms of PE—Don't Ignore These Warning Signs

Symptoms can be obvious or subtle, which makes PE particularly dangerous. Seek immediate medical attention if you experience:

⚠️ Emergency Warning Signs:

  • Sudden or worsening shortness of breath
  • Chest pain, especially sharp pain when breathing deeply
  • Rapid heart rate
  • Lightheadedness or fainting
  • Leg swelling, redness, or pain (possible DVT)
  • Coughing up blood (less common but serious)

Some individuals have no warning signs at all—and in rare cases, the first symptom is sudden death. This highlights the importance of understanding your personal risk.

Risk Factors You Might Not Know About

Blood clots can occur for many reasons beyond trauma or surgery. Factors that significantly increase your risk of DVT or PE include:

  • Long periods of immobility (long flights or car rides)
  • Recent surgery or hospitalization
  • Hormone therapy (birth control pills, testosterone)
  • Cancer or cancer treatment
  • Obesity and smoking
  • Pregnancy or recent childbirth
  • Genetic clotting disorders (Factor V Leiden, Protein C/S deficiency)

📊 Research Insight: A 2022 study in Blood Advances found that over 50% of patients with unprovoked PE—meaning there was no clear cause—actually had an underlying genetic tendency to form clots.

How Pulmonary Embolism Is Diagnosed

The gold standard for diagnosis is a CT Pulmonary Angiography (CTPA)—a specialized scan that uses contrast dye to reveal clots inside the lung arteries. It's fast, accurate, and widely available in emergency departments across the country.

Once a PE is diagnosed, most patients begin anticoagulation therapy ("blood thinners") immediately. These medications prevent new clots from forming and help the body naturally break down the existing clot.

But what if a clot is too large to wait?

When Blood Thinners Aren't Enough

Some pulmonary emboli are so large or dangerous that blood thinners alone cannot clear the blockage quickly enough. These include:

  • Massive PE (causing low blood pressure or cardiac collapse)
  • Submassive PE (causing strain on the right ventricle)
  • PE accompanied by severe symptoms or oxygen deprivation

In these cases, it's critical to remove the clot directly—and this is where minimally invasive thrombectomy becomes lifesaving.

Thrombectomy: A Modern, Minimally Invasive Breakthrough

Just a decade ago, removing a clot from the lungs required open surgery. Today, thanks to innovations in endovascular and interventional radiology, specialists like Dr. Komlos can remove life-threatening clots through a tiny puncture in the skin.

How Thrombectomy Works

  1. A thin catheter is placed into a vein—usually in the groin.
  2. Under X-ray guidance, the catheter is advanced through the heart and into the pulmonary arteries.
  3. Contrast dye maps the size and location of the clot.
  4. A specialized device suction removes or mechanically breaks apart the clot, restoring blood flow immediately.

⏱️ The entire procedure typically takes 30–40 minutes, and patients often feel relief right away.

This minimally invasive approach is safer, faster, and far more effective for large clots than relying on blood thinners alone.

Preventing Long-Term Complications: Understanding CTEPH

If a clot isn't fully cleared, some patients develop Chronic Thromboembolic Pulmonary Hypertension (CTEPH)—a type of dangerously high blood pressure in the lungs caused by lingering blockages.

  • CTEPH affects 3–4% of PE survivors
  • Can lead to progressive heart failure
  • Early thrombectomy may reduce this risk by restoring normal blood flow before permanent damage occurs

How Long Will You Need Blood Thinners?

Treatment duration depends on what caused your PE:

  • Provoked PE (surgery, travel, immobilization): typically 3–6 months
  • Unprovoked PE: often long-term therapy
  • Genetic clotting disorders or recurrent clots: lifelong treatment may be recommended

Your doctor will tailor your plan based on lifestyle, medical history, and risk of recurrence.

Why Minimally Invasive Solutions Matter

Minimally invasive procedures—like the thrombectomy techniques performed by Dr. Komlos—empower patients with:

  • ✅ Faster recovery
  • ✅ Less pain
  • ✅ Lower complication rates
  • ✅ Reduced need for open surgery
  • ✅ Better long-term outcomes

Dr. Komlos' expertise in pulmonary emboli, venous disease, and endovascular innovation allows patients to receive the most advanced, evidence-based care available today.

Final Thoughts

Pulmonary embolism is common, dangerous, and often misunderstood. But thanks to rapid imaging and minimally invasive thrombectomy, patients now have more effective treatment options than ever before.

⚠️ If you experience sudden shortness of breath, chest pain, dizziness, or leg swelling—do not wait. Seek emergency care immediately. Early diagnosis and treatment can save your life.

And whether you're planning a long trip or considering hormone therapy, understanding your risks is the first step in protecting your health.

Expert Care for Pulmonary Embolism & Vascular Emergencies

Dr. Fabio Komlos specializes in minimally invasive thrombectomy and advanced endovascular treatments for pulmonary embolism, offering life-saving solutions with faster recovery and better outcomes.

📞 (650) 404-8445

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FABIO KOMLOS, MD

Board-Certified Interventional Radiologist

Minimally Invasive • Patient-Centered • Innovation-Driven